Fave si, ma non per tutti

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Quando arriva questa stagione la mia casa si riempie di fave fresche considerate in famiglia una leccornia da gustare assieme ad un bel pezzetto di formaggio, un gustoso pecorino stagionato, un buon bicchiere di vino e perché no una fettina di buon salame (o sopressata per chi come me ha origini calabresi).

Avendo da sempre vissuto in una terra che è quella pugliese, però, le fave sono un alimento che amo consumare anche nel periodo invernale sotto forma di purè di fave, uno dei piatti poveri della tradizione, che si consuma accompagnandolo a deliziose cicorie selvatiche.

Perché le fave, come tutte le altre leguminose, possono consumarsi sia fresche che essiccate. In quest’ultimo caso previo ammollo e quasi sempre cotte.

Coltivata già in epoca biblica dagli Ebrei la fava, la leguminosa del genere Vicia faba, vede la sua cultura diffondersi presso gli egizi e i romani, ma anche presso i greci i quali utilizzavano tale frutto secco per votare, convinti che le anime dei defunti potessero reincarnarsi in esse.

Considerato, per secoli, il cibo dei poveri e per giunta tossico (sia nella sua versione fresca che secca), il consumo delle fave non è legato esclusivamente ad una questione di gusto, ma al fatto che alcuni soggetti, al di là del piacere o meno, non hanno proprio la possibilità di poterlo consumare.

Questo frutto, infatti, risulta molto dannoso per quei soggetti predisposti o affetti da una malattia molto grave detta favismo o anemia emolitica, una enzimopatia umana (la più comune), causata dal deficit genetico dell’enzima glucosio-6-fosfato-deidrogenasi, che serve a proteggere i globuli rossi dallo stress ossidativo.

Nel 2012 il Comitato Nazionale per la Sicurezza Alimentare aveva rilasciato un parere su alcune problemtiche relative al favismo (riprendendo quanto detto in una nota del 2008 dal CUDN- Commissione unica per la dietetica e la nutrizione) a seguito di una richiesta giunta alla Direzione generale per l’igiene e la sicurezza degli alimenti e la nutrizione con la quale si era chiesto di “verificare se negli ultimi anni (successivi al 2008 e successivi pertanto al parere del CUDN) fossero intervenuti elementi a carattere medico-scientifico tali da dimostrare che anche le inalazioni di pollini di fave e piselli potessero essere considerati fattori scatenanti di crisi emolitiche”.

Già le indicazioni del CUDN avevano messo in evidenza come l’ingestione di piselli e fagiolini, o l’inalazione dei loro pollini, non potessero essere considerate fattore scatenante di crisi emolitiche, quali quelle riconducibili al favismo e nonostante l’inalazione di polline nei campi di fave in fiore, potesse provocare malessere nei soggetti esposti, affetti da deficit di G6PD, non erano state trovate prove scientifiche sufficienti a correlare l’inalazione di polline con lo scatenamento delle crisi emolitiche.

Il parere rilasciato nel 2012 secondo il quale dagli  studi condotti nel 1979, nel 1983 e nel 2009 si evinceva che “Le rare segnalazioni esistenti non sono tuttavia sufficienti per poter ragionevolmente correlare lo scatenamento di una crisi emolitica all’inalazione di pollini di fave” non ha fatto altro che confermare nuovamente la nota precedente.

Favismo o G6PD deficit : facciamo il punto

I soggetti colpiti dal favismo (400 milioni di persone al mondo, circa 400.000 in Italia con maggiore incidenza in Sardegna, nel Delta del Po e nella zona ex-paludosa del Veneto orientale) presentano una malattia genetica ereditaria causata da una carenza dell’enzima glucosio-6-fosfato deidrogenasi normalmente presente nei globuli rossi, da qui il nome di deficit G6PD (anche detto G6PDH), sintetizzato da un gene localizzato sul cromosoma X ed essenziale per la vitalità degli eritrociti e in particolare per i processi ossidativi che in essi si svolgono.  Il deficit, pertanto, si trasmette con un’ereditarietà legata al sesso, con interessamento prevalente dei maschi emizigoti e delle femmine omozigoti.

Di solito nei maschi il deficit enzimatico è decisamente marcato, mentre le femmine possono essere sia portatrici che affette.

Nei soggetti portatori della patologia non si riesce a mantenere un adeguato livello di glutatione ridotto negli eritrociti (globuli rossi) che per tale motivo vanno incontro a crisi emolitiche scatenate da reazioni ossidative a loro volte legate a ingestione di fave,  assunzione di alcuni farmaci quali sulfamidici, salicilici, chinidina, ecc., o a causa di infezioni.

Nel caso specifico delle fave è l’ingestione di alcune sostanze in esse presenti, la vicina e la convicina (beta-glucosidi della pirimidina presenti nei cotiledoni del frutto, ma non nei fiori, con funzioni protettive contro i numerosi patogeni che attaccano la pianta) a poter scatenare, dopo circa 12-48 ore, manifestazioni cliniche di entità variabile con crisi emolitiche (e distruzione degli interi globuli rossi), conseguente ittero per accumulo di bilirubina, respiro frequente, difficoltoso e, nei casi più gravi, insufficienza renale acuta.

Secondo vari studi non tutti i soggetti affetti da deficit di G6PD manifestano episodi emolitici conclamati, infatti,  i bambini sembrano essere più soggetti a crisi faviche, probabilmente per la relativa maggiore esposizione correlata alla minore superficie corporea. Come del resto la gravità della sintomatologia può dipendere da una concomitanza di diversi fattori, quali ad esempio, il livello di attività enzimatica, le caratteristiche metaboliche individuali, lo stato di salute generale, la quantità di fave ingerite o gli eventuali trattamenti ai quali le stesse possono essere sottoposte.

Proprio in virtù di quanto appena detto, si è riscontrato, infatti, che le fave fresche risultino maggiormente dannose rispetto a quelle trattate (ad esempio rispetto alle fave sottoposte a cottura), o che le fave “giovani” siano più rischiose per la presenza in esse di una percentuale maggiore dei glucosidi vicina e convicina rispetto alle fave più mature dove il loro quantitativo tende a ridursi progressivamente.

Conclusioni

Come indicato nelle Linee guida al Deficit di G6PD dell’Associazione Italiana Favismo, in molti ospedali,  per questa malattia è stato ormai introdotto lo screening neonatale. E comunque la diagnosi per individuare l’eventuale carenza enzimatica nei globuli rossi viene fatta attraverso un semplice prelievo del sangue.

Esistono più di 200 varianti di questo deficit in continua evoluzione, la cui reazione può risultare imprevedibile in quanto accentuata dallo stato psicofisico generale del soggetto colpito. È importante avere sempre molta cautela nei confronti di questa patologia, poiché una delle caratteristiche del favismo è quella di rendere il soggetto asintomatico fino a quando, lo stesso, non entra in contatto con agenti ossidanti quali gli alimenti e i farmaci su menzionati.

A casa siamo soliti fare sempre un gioco. Chi ne sbuccia di più (di fave), ne mangia di più. Ma è inutile dirlo, io non vinco mai. Perché quando sbuccio i robusti baccelli dalle estremità appuntite di questo frutto la cosa da cui sono più attirata – e soprattutto distratta – è lo strato spugnoso e biancastro, presente al loro interno, capace di ospitare dai 5 ai 10 semi piatti e arrotondati di colore verde, rossastro, brunastro o violaceo (a seconda della varietà), nel quale affondo le dita… quasi fosse un anti stress. Provare per credere!

© Produzione riservata

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Dr.ssa Sabina Rubini

Biologa ed Esperta in Sicurezza degli Alimenti
Consulente Aziendale

Co-founder ISQAlimenti.it

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  212. What’s up?

    I found this article very interesting…please read!

    Do you remember the blockbuster hit film The Matrix that was released in 1999? You may not know this, but it has deep spiritual implications concerning the times we are living in and Bible prophecy.

    It tells a story of how these “agents” are trying to turn us into machines. We are closer then ever before for this to become a reality when they cause us to receive an implantable microchip in our body during a time when physical money will be no more.

    You may have seen on NBC news concerning the implantable RFID microchip that some people are getting put in their hand to make purchases, but did you know this microchip matches perfectly with prophecy in the Bible?

    “He (the false prophet who deceives many by his miracles) causes all, both small and great, rich and poor, free and slave, to receive a mark on their right hand or on their foreheads, and that no one may buy or sell except one who has the mark or the name of the beast, or the number of his name…

    You also may have heard of the legendary number “666” that people have been speculating for possibly thousands of years on what it actually means. This article shares something I haven’t seen before, and I don’t think there could be any better explanation for what it means to calculate 666. This is no hoax. Very fascinating stuff!

    …Here is wisdom. Let him who has understanding calculate the number of the beast, for it is the number of a man: His number is 666″ (Revelation 13:16-18 NKJV).

    To see all the details showing why the Bible foretold of all these things, check out this article!

    Article: https://biblewoke.com/rfid-mark-of-the-beast-666-revealed

    GOD is sending out His end time warning:

    “Then a third angel followed them, saying with a loud voice, ‘If anyone worships the beast and his image, and receives his mark on his forehead or on his hand, he himself shall also drink of the wine of the wrath of God, which is poured out full strength into the cup of His indignation. He shall be tormented with fire and brimstone in the presence of the holy angels and in the presence of the Lamb. And the smoke of their torment ascends forever and ever; and they have no rest day or night, who worship the beast and his image, and whoever receives the mark of his name'” (Revelation 14:9-11).

    In the Islamic religion they have man called the Mahdi who is known as their messiah of whom they are waiting to take the stage. There are many testimonies from people online who believe this man will be Barack Obama who is to be the biblical Antichrist based off dreams they have received. I myself have had strange dreams about him like no other person. So much so that I decided to share this information.

    He came on stage claiming to be a Christian with no affiliation to the Muslim faith…

    “In our lives, Michelle and I have been strengthened by our Christian faith. But there have been times where my faith has been questioned — by people who don’t know me — or they’ve said that I adhere to a different religion, as if that were somehow a bad thing,” – Barack Obama

    …but was later revealed by his own family members that he indeed is a devout Muslim.

    So what’s in the name? The meaning of someones name can say a lot about a person. God throughout history has given names to people that have a specific meaning tied to their lives. How about the name Barack Obama? Let us take a look at what may be hiding beneath the surface…

    “And He (Jesus) said to them (His disciples), ‘I saw Satan fall like lightning from heaven'” (Luke 10:18).

    In the Hebrew language we can uncover the meaning behind the name Barack Obama.

    Barack, also transliterated as Baraq, in Hebrew is: lightning

    baraq – Biblical definition:

    From Strongs H1299; lightning; by analogy a gleam; concretely a flashing sword: – bright, glitter (-ing, sword), lightning. (Strongs Hebrew word H1300 baraq baw-rawk’)

    Barak ‘O’bamah, The use of bamah is used to refer to the “heights” of Heaven.

    bamah – Biblical definition:

    From an unused root (meaning to be high); an elevation: – height, high place, wave. (Strongs Hebrew word H1116 bamah baw-maw’)

    The day following the election of Barack Obama (11/04/08), the winning pick 3 lotto numbers in Illinois (Obama’s home state) for 11/5/08 were 666.

    Obama was a U.S. senator for Illinois, and his zip code was 60606.

    Seek Jesus while He may be found…repent, confess and forsake your sins and trust in the savior! Jesus says we must be born again by His Holy Spirit to enter the kingdom of God…God bless!

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  254. Description de PhenQ :

    “PhenQ” est un produit qui combine les bienfaits de
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    poids optimale!
    Evaluation de PhenQ :

    “PhenQ” est un comprimé amincissant qui additionne les effets minceurs positifs de plusieurs compléments
    alimentaires pour vous offrir un résultat jusqu’ici inégalé en ce qui concerne la perte de poids!

    En effet, ce nouveau complément alimentaire amaigrissant a, de part sa formule innovante,
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    Quels sont les propriétés du produit?

    PhenQ“PhenQ” est formulé de façon à nous procurer toute
    une palette d’actions qui devraient favoriser la perte de poids.

    Voici donc la liste des effets bénéfiques de
    cette pilule minceur :

    – Un effet qui stoppe la production de graisses!
    – Un effet qui booste le métabolisme pour brûler les graisses!

    – Un effet coupe-faim qui supprime l’appétit!
    – Un effet qui donne au corps un surplus d’énergie!

    – Un effet qui agit positivement sur l’humeur!
    Quels sont les ingrédients contenus dans “PHENQ”?

    “Phenq” est un complément alimentaire fabriqué avec
    des ingrédients de qualités pharmaceutiques dans des installations qui respectent les normes pharmaceutiques américaines et britanniques strictes,
    ces installations sont en plus approuvées par la FDA
    (Food and Drug Administration)!

    Les ingrédients qui entrent dans la composition de
    ce comprimé minceur sont :

    1. Le Capsimax en poudre composé d’un mélange de capsicum, pipérine, caféine, et niacine.

    – Le Capsicum (extrait de piment) va apporter ses effets brûle-graisses.

    – La Pipérine (poivre noir) va favoriser la perte
    de poids en augmentant la température corporelle.
    – La Caféine va apporter ses effets stimulants et diurétiques.

    – La Niacine (vitamine B3) va favoriser la production d’énergie.

    2. Le Carbonate de Calcium.

    – Le Calcium est bon pour les os et est essentiel au bon fonctionnement de vos
    cellules.

    3. Le Picolinate de Chrome.

    – Le Picolinate de Chrome favorise la réduction en glucides et aide le corps à contrôler le niveau de sucre dans le sang.

    4. La Caféine.

    – La Caféine est un stimulant naturel qui réduit la fatigue, augmente les performances physiques
    et la concentration.
    – La Caféine augmente aussi le niveau de thermogenèse
    et favorise donc la perte de poids.

    5. a-Lacy Reset®.

    – a-Lacy Reset® est un complexe breveté composé d’Acide alpha-lipoïque, de
    Cystéine et de magnésium. Cette synergie règle l’équilibre des cellules en contrôlant et en neutralisant
    un grand nombre de radicaux liés aux entraînements intenses, au vieillissement et
    aux troubles généraux.

    6. Le Nopal.

    – Le Nopal, cactus extrêmement riche en acides aminés est
    une source élevée en fibres qui aide au contrôle de l’appétit.

    – Le Nopal contribue également à réduire la rétention d’eau.

    7. L-Carnitine.

    – L-Carnitine est un acide aminé naturel qui favorise la transformation des réserves graisseuses en énergie.

    Comment ça fonctionne?

    “PhenQ” va avoir une action bénéfique sur l’amaigrissement en agissant
    sur plusieurs facteurs responsables de la prise de poids.

    – Le métabolisme lent

    Ce complément alimentaire va booster le métabolisme dans le but d’accélérer la dépense des calories.

    – Les graisses

    Il va diminuer la production de nouvelles graisses et va en plus
    favoriser la combustion des graisses stockées grâce à un effet thermogénique puissant.

    – Les fringales

    Cette pilule minceur va également aider au contrôle
    de l’appétit avec son effet coupe faim.

    – La fatigue

    Grâce à un effet boosteur d’énergie, cette gélule de perte de poids va avoir l’avantage de recharger vos batteries tout en luttant contre la dépression et le stress.

    La combinaison de ces effets d’amincissement fait de “PhenQ” un allié
    minceur de poids capable de vous aider de façon effective dans votre démarche
    de perte de poids!
    Posologie :

    Le “Phen Q” se présente sous forme de comprimés minceurs, il
    est commercialisé en bouteille de 60 comprimés.

    La pilule de “PHEN Q” est facile à avaler et se prend deux fois par jours,
    lors du petit déjeuner et du déjeuner.
    Informations Complémentaires :

    PhenQLes livraisons sont rapides et sécurisées, elles sont en plus gratuites à
    partir de l’achat de deux bouteilles de ce comprimé minceur.

    Le support clientèle est convivial et efficace.
    Il est accessible via un système de chat direct, via
    un formulaire en ligne, par téléphone et même avec l’application mobile WhatsApp.

    Le complément alimentaire “PhenQ” est une réelle évolution dans les suppléments minceurs puisqu’il va vous apporter des effets brûleur de graisse efficaces, des
    effets coupe-faim, des effets pour empêcher la production de nouvelles
    graisses ainsi que des effets boosteur d’énergie!

    Inconvénients de PhenQ :

    “PhenQ” ne convient pas aux femmes enceintes ou qui allaitent, aux personnes
    de moins de 18 ans, aux personnes souffrant de dépression, de
    diabète, de troubles endocriniens, de maladies auto-immunes,
    d’hypertrophie prostatique, de maladie du foie, de maladie du
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    Si vous avez des soucis médicaux ou si vous êtes sous prescription médicale, il est conseillé de
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    Il est déconseillé de prendre un comprimé
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    trouver le sommeil.
    Réputation de PhenQ :

    Ce complément minceur jouit d’une assez bonne réputation sur
    Internet, et, l’opinion qui se forge en se basant sur les différents avis, témoignages, critiques et commentaires disponibles sur la toile, est que “PHEN Q” apparait comme étant
    une solution minceur qui procure de très bons résultats!

    Wolfson Berg Limited a une excellente réputation, son nom est
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    Conclusion pour PhenQ :

    PhenQ FemmeComme je ne cesse de le répéter, je ne suis
    pas friand de ces pilules pour maigrir qui sont pour la plupart des arnaques et parfois
    même se révèlent néfastes pour la santé.

    Ceci étant dit, je dois avouer que les avis à propos
    du comprimé minceur “PhenQ” sont assez bons, ce qui me force à approuver et à recommander ce produit.

    Mais gardez bien à l’esprit que même si ce produit minceur est efficace, il
    ne vous offrira qu’un coup de pouce pour perdre du poids
    et, un style de vie sain ainsi qu’une alimentation saine
    sera toujours la seule solution efficace sur le long terme!

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